When Wolverine discovers an old friend is missing, his visit to Canada soon transforms into a hairy situation. The Wendigo virus is running rampant, changing people into flesh-eating monsters! Now, the X-Men and Alpha Flight must fight to stop the growing tide of Wendigos from consuming everything and everyone in their path -- a task made harder when an X-Man falls prey to the deadly disease! Desperate, the X-Men take the fight to the Spirit Realm, but how do the Great Beasts fit into this mayhem? And will even the combined forces of the X-Men and Alpha Flight be enough to save Canada from this cannibalistic plague? Plus: Iceman, Firestar and Spider-Man must renew their amazing friendship to save New York City!